Browse over 9,000 car reviews

Lexus IS vs Mercedes-Benz CLS-Class

What's the difference?

VS
Lexus IS
Lexus IS

$52,990 - $72,900

2021 price

Mercedes-Benz CLS-Class
Mercedes-Benz CLS-Class

$179,717 - $184,800

2022 price

Summary

2021 Lexus IS
2022 Mercedes-Benz CLS-Class
Safety Rating

Engine Type
Inline 4, 2.5L

Twin Turbo 6, 3.0L
Fuel Type
Premium Unleaded/Electric

Premium Unleaded/Electric
Fuel Efficiency
4.9L/100km (combined)

9.2L/100km (combined)
Seating
5

5
Dislikes
  • Slow
  • Busy interior design
  • Fiddly and over-complicated software

  • Compromised rear-seat room
  • Pricier than rivals
  • Unergonomic steering wheel controls
2021 Lexus IS Summary

One question frequently discussed in the skunkworks of the CarsGuide office is: What exactly does Lexus stand for?

When the brand debuted its original export-market IS sedan in 1999 the messaging was more or less clear: Toyota’s premium sub-brand was here to be a Japanese BMW.

The brand even employed Nobuaki Katayama – chief engineer on the iconic Corolla AE86 program – to again take the reins of its small rear-wheel drive sedan program.

As the years went on though, Lexus changed. Fundamentally geared toward the US market, the second-generation (wild IS F aside) became a bit more sedate and softer around the edges, while the third generation strayed even further from the sedan’s performance-inspired roots, leaning into a plush interior, hybrid drive, and even CVT transmissions.

This brings us to today’s Lexus IS. Essentially a heavy facelift of the third generation (which arrived back in 2013), the brand has “reimagined” its core sedan with a tweaked design and updated technology for 2021.

Is it enough to keep it relevant against its ever-present European rivals and the newly arrived threat from Hyundai’s Genesis G70? I took a signature IS300h hybrid for a week to find out.

View full pricing & specs
2022 Mercedes-Benz CLS-Class Summary

Mercedes-Benz loves to fill a niche. This is the company, after all, that has a coupe version of its GLC and GLE SUVS, four-door coupes ranging in size from the CLA to the AMG GT 4-door, and enough electric vehicles to make Tesla jealous.

The nichest of all though, might the CLS, which has been updated for the 2022 model year.

Positioned above the E-Class but below the S-Class in the line-up as a sporty sedan for customers after a blend of style, technology and performance, the new CLS is available in just one engine now, while styling and equipment have also been tweaked in the update.

Can the CLS earn its place in the Mercedes line-up or is it destined to be a bit player amongst more popular models?

View full pricing & specs

Deep dive comparison

2021 Lexus IS 2022 Mercedes-Benz CLS-Class

Change vehicle