Lexus IS vs Mercedes-Benz S-Class

What's the difference?

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Lexus IS
Lexus IS

$42,999 - $72,999

2021 price

Mercedes-Benz S-Class
Mercedes-Benz S-Class

$117,488 - $139,800

2021 price

Summary

2021 Lexus IS
2021 Mercedes-Benz S-Class
Safety Rating

Engine Type
Inline 4, 2.5L

Twin Turbo V6, 3.0L
Fuel Type
Premium Unleaded/Electric

Premium Unleaded Petrol
Fuel Efficiency
4.9L/100km (combined)

8.4L/100km (combined)
Seating
5

5
Dislikes
  • Slow
  • Busy interior design
  • Fiddly and over-complicated software

  • Price of entry prohibitive for most
  • 3D instrumentation can make you woozy
  • A tad conservative in design
2021 Lexus IS Summary

One question frequently discussed in the skunkworks of the CarsGuide office is: What exactly does Lexus stand for?

When the brand debuted its original export-market IS sedan in 1999 the messaging was more or less clear: Toyota’s premium sub-brand was here to be a Japanese BMW.

The brand even employed Nobuaki Katayama – chief engineer on the iconic Corolla AE86 program – to again take the reins of its small rear-wheel drive sedan program.

As the years went on though, Lexus changed. Fundamentally geared toward the US market, the second-generation (wild IS F aside) became a bit more sedate and softer around the edges, while the third generation strayed even further from the sedan’s performance-inspired roots, leaning into a plush interior, hybrid drive, and even CVT transmissions.

This brings us to today’s Lexus IS. Essentially a heavy facelift of the third generation (which arrived back in 2013), the brand has “reimagined” its core sedan with a tweaked design and updated technology for 2021.

Is it enough to keep it relevant against its ever-present European rivals and the newly arrived threat from Hyundai’s Genesis G70? I took a signature IS300h hybrid for a week to find out.

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2021 Mercedes-Benz S-Class Summary

It's only in the running for the title of world's best luxury car. No biggie here, then.

Like Rolex and Concorde, S-Class has become a byword for ultimate, and deserved or not, the Mercedes-Benz defines its segment despite the best efforts of the BMW 7 Series, Audi A8, Lexus LS and (sadly now-defunct) Jaguar XJ, as well as pointing the way forward with new technologies that eventually trickle down to more proletarian models.

Replacing the half-million selling W222 unveiled in 2013, the W223 is the latest in a long line since the first W187 Ponton debuted in 1951, and includes the famous ‘Finnies' and Stroke-8 models that followed immediately afterwards, but it is the 1972 W116 that really set the template.

Now, seven generations in, the 2021 S-Class is all-new again, with progressive safety and interior features that should help keep it Australia's bestselling full-sized upper-luxury sedan.

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Deep dive comparison

2021 Lexus IS 2021 Mercedes-Benz S-Class

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