Lexus IS vs Mercedes-Benz Cle53

What's the difference?

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Lexus IS
Lexus IS

$42,999 - $72,999

2021 price

Mercedes-Benz Cle53
Mercedes-Benz Cle53

2025 price

Summary

2021 Lexus IS
2025 Mercedes-Benz Cle53
Safety Rating

Engine Type
Inline 4, 2.5L

Turbo 6, 3.0L
Fuel Type
Premium Unleaded/Electric

Premium Unleaded Petrol
Fuel Efficiency
4.9L/100km (combined)

9.6L/100km (combined)
Seating
5

4
Dislikes
  • Slow
  • Busy interior design
  • Fiddly and over-complicated software

  • C-Class rather than classier E-Class dash lowers the vibe
  • Interior quality isn’t quite as vault-like as we’d like
  • Tyre noise intrusion
2021 Lexus IS Summary

One question frequently discussed in the skunkworks of the CarsGuide office is: What exactly does Lexus stand for?

When the brand debuted its original export-market IS sedan in 1999 the messaging was more or less clear: Toyota’s premium sub-brand was here to be a Japanese BMW.

The brand even employed Nobuaki Katayama – chief engineer on the iconic Corolla AE86 program – to again take the reins of its small rear-wheel drive sedan program.

As the years went on though, Lexus changed. Fundamentally geared toward the US market, the second-generation (wild IS F aside) became a bit more sedate and softer around the edges, while the third generation strayed even further from the sedan’s performance-inspired roots, leaning into a plush interior, hybrid drive, and even CVT transmissions.

This brings us to today’s Lexus IS. Essentially a heavy facelift of the third generation (which arrived back in 2013), the brand has “reimagined” its core sedan with a tweaked design and updated technology for 2021.

Is it enough to keep it relevant against its ever-present European rivals and the newly arrived threat from Hyundai’s Genesis G70? I took a signature IS300h hybrid for a week to find out.

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2025 Mercedes-Benz Cle53 Summary

You’re looking at what Mercedes-Benz dubs “The AMG for all occasions”, the CLE 53.

Now, in case you haven’t been paying attention, the CLE replaces both the previous C-Class and E-Class coupes, so we’re talking about a relatively practical two-door four-seater here.

So, 53? Not the full-fat 63 flagship, then (that’s coming eventually), but something that comes close to the slightly more-powerful (and a bit more expensive) Audi RS5 and BMW M4 range-topping alternatives.

Like Goldilocks’ preferred porridge, this particular flavour of coupe is meant to leave well-heeled enthusiasts not too hot or too bothered, meaning it’s been engineered to be refreshingly refined as well as rousingly rapid.

Is the AMG CLE 53 just right, then? Time to find out.

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Deep dive comparison

2021 Lexus IS 2025 Mercedes-Benz Cle53

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