E10 unleaded in 2013 Audi A5

Yes, you can use E10 in your A5, but because E10 packs less energy than 95-octane premium unleaded the performance of your car will be diminished. The difference can be between one and eight percent, so you will consume more E10 to achieve the same performance. You won't do your engine any harm by using it, so try a tank of E10 and measure the difference in consumption that you get.