Audi S5 vs Mercedes-AMG E63

What's the difference?

VS
Audi S5
Audi S5

$99,900 - $134,515

2025 price

Mercedes-AMG E63
Mercedes-AMG E63

2021 price

Summary

2025 Audi S5
2021 Mercedes-AMG E63
Safety Rating

Engine Type
Turbo 4, 2.0L

Twin Turbo V8, 4.0L
Fuel Type
Premium Unleaded/Electric

Premium Unleaded Petrol
Fuel Efficiency
6.9L/100km (combined)

12.3L/100km (combined)
Seating
5

5
Dislikes
  • Loses some interior simplicity 
  • Edition One not a permanent fixture
  • Having to wait for more variants

  • Fiddly steering wheel controllers
  • Tight rear door apertures
  • Thirsty
2025 Audi S5 Summary

The Audi A5 has done something naughty. It’s replaced the Audi A4.

Or at least that’s the case for now after the Ingolstadt brand made a bit of a mess of its naming strategy.

Essentially, the Audi A5 is now available as a sedan or a wagon, and the next A4 coming soon will be electric. The previous A5 was a swoopier two-door coupe or four-door gran coupe style model. So the A5 is now effectively Audi’s main BMW 3 Series or Mercedes C-Class and CLA rival.

Plus, the Audi S5 is also here to cater to performance car fans.

Can a new platform, a sleek, fresh look and a techy interior do the job?

We’ve been pedalling around the Victorian countryside in the hopes of finding out.

Stick with me, and I reckon we’ll get to the bottom of it. The question about the car, that is, not the bottom of Victoria.

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2021 Mercedes-AMG E63 Summary

Feels like lately all the Mercedes-AMG buzz has been at the smaller end of the scale.

Most recently, the screaming GLA 45 S has arrived in Australia, pumping out more kilowatts and newton-metres than any compact SUV has a right to.

But here, we're doubling the cylinder count to eight, arranging them in a vee, and lighting the wick on AMG's powerhouse mid-size sedan, the recently upgraded E 63 S.

While the ferocious twin-turbo V8 and the rest of this beast's powertrain are unchanged, the car has been brought up to speed with some aero-focused styling tweaks, Merc's latest 'Widescreen' digital cockpit, as well as the MBUX multimedia system, and a tricky new multi-function sports steering wheel.

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Deep dive comparison

2025 Audi S5 2021 Mercedes-AMG E63

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