Mercedes-Benz S450 vs Audi RS6

What's the difference?

VS
Mercedes-Benz S450
Mercedes-Benz S450

$117,488 - $139,800

2021 price

Audi RS6
Audi RS6

$252,600 - $399,000

2026 price

Summary

2021 Mercedes-Benz S450
2026 Audi RS6
Safety Rating

Engine Type
Twin Turbo V6, 3.0L

Twin Turbo V8, 4.0L
Fuel Type
Premium Unleaded Petrol

Premium Unleaded Petrol
Fuel Efficiency
8.4L/100km (combined)

11.8L/100km (combined)
Seating
5

5
Dislikes
  • Price of entry prohibitive for most
  • 3D instrumentation can make you woozy
  • A tad conservative in design

  • Unbelievable price over standard RS6
  • You probably won’t ever see one
  • Everyone will look at you
2021 Mercedes-Benz S450 Summary

It's only in the running for the title of world's best luxury car. No biggie here, then.

Like Rolex and Concorde, S-Class has become a byword for ultimate, and deserved or not, the Mercedes-Benz defines its segment despite the best efforts of the BMW 7 Series, Audi A8, Lexus LS and (sadly now-defunct) Jaguar XJ, as well as pointing the way forward with new technologies that eventually trickle down to more proletarian models.

Replacing the half-million selling W222 unveiled in 2013, the W223 is the latest in a long line since the first W187 Ponton debuted in 1951, and includes the famous ‘Finnies' and Stroke-8 models that followed immediately afterwards, but it is the 1972 W116 that really set the template.

Now, seven generations in, the 2021 S-Class is all-new again, with progressive safety and interior features that should help keep it Australia's bestselling full-sized upper-luxury sedan.

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2026 Audi RS6 Summary

When I say this is a rare review, I’m talking about the kind of rare that means you can’t even buy the car you’re reading about.

The 2026 Audi RS6 Avant GT you’re looking at in the pictures around this story is number 248 of 660. That’s six-hundred and sixty worldwide.

In Australia, there are only 22 RS6 GTs, and they’re all sold - at exorbitant prices, mind you, but we’ll get to that.

The RS6 GT is essentially a production version of the Audi RS6 GTO concept, built in 2020 and inspired by the Audi 90 quattro IMSA GTO race car, which means the RS6 GT carries a lot of ‘90 GTO’ in the way it looks. More on that shortly.

Aside from its extremely limited availability and its design package, there are some mechanical changes to increase the appeal of the RS6 GT, though whether any of its owners will put the on-road (or on-track) ability of this special wagon from Ingolstadt to the test remains to be seen.

A couple of days to live with one of the few RS6 GTs in Australia should reveal how special this car feels, and result in at least one example of the rarity being driven good and proper.

@carsguide.com.au Hens’ teeth have nothing on the 2026 Audi RS6 Avant GT. #audi #rs6 #audirs6 #cartok #fyp ♬ original sound  - CarsGuide.com.au
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Deep dive comparison

2021 Mercedes-Benz S450 2026 Audi RS6

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