Audi S5 vs Mercedes-Benz S600

What's the difference?

VS
Audi S5
Audi S5

$97,990 - $129,990

2025 price

Mercedes-Benz S600
Mercedes-Benz S600

2018 price

Summary

2025 Audi S5
2018 Mercedes-Benz S600
Safety Rating

Engine Type
Turbo 4, 2.0L

Fuel Type
Premium Unleaded/Electric

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Fuel Efficiency
6.9L/100km (combined)

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Seating
5

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Dislikes
  • Loses some interior simplicity 
  • Edition One not a permanent fixture
  • Having to wait for more variants

  • Some terseness from run-flat tyres
  • Controls could be simpler
  • Non L models not that spacious in the back
2025 Audi S5 Summary

The Audi A5 has done something naughty. It’s replaced the Audi A4.

Or at least that’s the case for now after the Ingolstadt brand made a bit of a mess of its naming strategy.

Essentially, the Audi A5 is now available as a sedan or a wagon, and the next A4 coming soon will be electric. The previous A5 was a swoopier two-door coupe or four-door gran coupe style model. So the A5 is now effectively Audi’s main BMW 3 Series or Mercedes C-Class and CLA rival.

Plus, the Audi S5 is also here to cater to performance car fans.

Can a new platform, a sleek, fresh look and a techy interior do the job?

We’ve been pedalling around the Victorian countryside in the hopes of finding out.

Stick with me, and I reckon we’ll get to the bottom of it. The question about the car, that is, not the bottom of Victoria.

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2018 Mercedes-Benz S600 Summary

Imagine a car that can pretty much drive itself, if you let it. And it’ll do that while you get a massage, pump some Beyonce, and enjoy the fragrance of a field full of flowers… And then, it can teach you to do stretches and exercises in the driver’s seat.

It may sound like fictional fiction, but it’s factual fact. And it’s the Mercedes-Benz S-Class 2018 model, which has taken the so-called ‘wellbeing’ of the driver to a new level.

The facelifted model has seen plenty of styling changes and some tech upgrades, and while making the flagship car in a particular brand’s line-up is often a task fraught with issues, the German company’s big, expensive, luxurious, limousine is undoubtedly a more thoughtful car for 2018.

But just remember, its predecessor was considered - at least for a little while - as the best car in the world by some automotive journalists. 

Now Mercedes-Benz has updated it, and it reckons it’s better than before, bringing a bunch of new technology, new engines, a reworked model range and, perhaps not essentially, but still pleasantly, lower pricing.

Read on to see how Beyonce factors into the equation.

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Deep dive comparison

2025 Audi S5 2018 Mercedes-Benz S600

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