Audi S5 vs Mercedes-Benz S-Class

What's the difference?

VS
Audi S5
Audi S5

$99,900 - $134,515

2025 price

Mercedes-Benz S-Class
Mercedes-Benz S-Class

$118,880 - $249,800

2021 price

Summary

2025 Audi S5
2021 Mercedes-Benz S-Class
Safety Rating

Engine Type
Turbo 4, 2.0L

Twin Turbo V6, 3.0L
Fuel Type
Premium Unleaded/Electric

Premium Unleaded Petrol
Fuel Efficiency
6.9L/100km (combined)

8.4L/100km (combined)
Seating
5

5
Dislikes
  • Loses some interior simplicity 
  • Edition One not a permanent fixture
  • Having to wait for more variants

  • Price of entry prohibitive for most
  • 3D instrumentation can make you woozy
  • A tad conservative in design
2025 Audi S5 Summary

The Audi A5 has done something naughty. It’s replaced the Audi A4.

Or at least that’s the case for now after the Ingolstadt brand made a bit of a mess of its naming strategy.

Essentially, the Audi A5 is now available as a sedan or a wagon, and the next A4 coming soon will be electric. The previous A5 was a swoopier two-door coupe or four-door gran coupe style model. So the A5 is now effectively Audi’s main BMW 3 Series or Mercedes C-Class and CLA rival.

Plus, the Audi S5 is also here to cater to performance car fans.

Can a new platform, a sleek, fresh look and a techy interior do the job?

We’ve been pedalling around the Victorian countryside in the hopes of finding out.

Stick with me, and I reckon we’ll get to the bottom of it. The question about the car, that is, not the bottom of Victoria.

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2021 Mercedes-Benz S-Class Summary

It's only in the running for the title of world's best luxury car. No biggie here, then.

Like Rolex and Concorde, S-Class has become a byword for ultimate, and deserved or not, the Mercedes-Benz defines its segment despite the best efforts of the BMW 7 Series, Audi A8, Lexus LS and (sadly now-defunct) Jaguar XJ, as well as pointing the way forward with new technologies that eventually trickle down to more proletarian models.

Replacing the half-million selling W222 unveiled in 2013, the W223 is the latest in a long line since the first W187 Ponton debuted in 1951, and includes the famous ‘Finnies' and Stroke-8 models that followed immediately afterwards, but it is the 1972 W116 that really set the template.

Now, seven generations in, the 2021 S-Class is all-new again, with progressive safety and interior features that should help keep it Australia's bestselling full-sized upper-luxury sedan.

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Deep dive comparison

2025 Audi S5 2021 Mercedes-Benz S-Class

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