Lexus NX450H+ vs Mercedes-Benz C350 E

What's the difference?

VS
Lexus NX450H+
Lexus NX450H+

$82,990 - $103,598

2025 price

Mercedes-Benz C350 E
Mercedes-Benz C350 E

$99,500 - $99,500

2026 price

Summary

2025 Lexus NX450H+
2026 Mercedes-Benz C350 E
Safety Rating

Engine Type
Inline 4, 2.5L

Turbo 4, 2.0L
Fuel Type
Premium Unleaded/Electric

Premium Unleaded/Electric
Fuel Efficiency
1.3L/100km (combined)

1.5L/100km (combined)
Seating
5

5
Dislikes
  • Misses out on a few items for a flagship model
  • Not as flashy inside as rivals
  • Plug-in hybrid powertrain won't win over everyone

  • Transmission hesitation
  • DC charging only optional 
  • Servicing costs
2025 Lexus NX450H+ Summary

The Lexus NX 450h+ F Sport is a well-specified and plush-looking medium SUV that has a plug-in hybrid powertrain - a first for the brand.

On paper, it seems to tick the boxes for size, luxury and efficiency but we've been testing the flagship grade to see if it's a winning combo in real life.

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2026 Mercedes-Benz C350 E Summary

They're doing it again! Actually they've been doing it again for a bit now. It’s Mercedes-Benz Australia and plug-in hybrid tech.

The Ross and Rachel, or Jim and Pam of the premium automotive world.

It's been a will they, won't they for a while, and in the past Mercedes has dipped its proverbial plug into the electrons a few times and gotten cold feet.

But now it says it’s all in. There are others, the GLA and GLC SUVs, plus there’s the new C63 performance car, but this one feels like a bit of an arrival.

Yeah, the C-Class is no longer the Mercedes-Benz in terms of sales, but it might be the best way to make the most of a bit of battery power.

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Deep dive comparison

2025 Lexus NX450H+ 2026 Mercedes-Benz C350 E

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