My 2014 Isuzu MU-X front row AC doesn’t blow sometimes. The rear works fine and is cool, but the fan at the front doesn’t engage. I can feel a slight draft coming through the vents. Sometimes it’ll work right away, sometimes it’ll take a couple minutes and other times recently it won’t work at all, over a 20 minute drive.
Air-conditioning relies on fans as well as the actual refrigeration system to move the chilled air around the cabin. If the fan isn’t working, that won’t happen. So a check of the fan in question would be a good place to start. Perhaps there’s a wiring fault, maybe the fan is intermittently failing to kick in.
There’s another possibility, too, and it’s more common than you might think. Some air-con systems tend to build up ice inside the system’s plumbing. If that happens, you’ll suddenly get no air-con and possibly even zero airflow through he vents as the ice blocks the trunking completely. The solution is to turn the system off at that point, allow everything to thaw and then turn it back on. Try that process next time the vents fail to see if that fixes it (temporarily).